RGNCY-0003 (TLR7-8 inhibitor)
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SMILES: CCCCC(N1CC(C)(O)C)=NC2=C1C3=CC=C(C(OC)=O)C=C3N=C2N
Systematic Name: methyl 4-amino-2-butyl-1-(2-hydroxy-2-methylpropyl)-1H-imidazo[4,5-c]quinoline-7-carboxylate
Molecular Weight: 370.45
PMID: 24383475
Reference: Schiaffo, Charles E., et al. "Structure–Activity Relationship Analysis of Imidazoquinolines with Toll-like Receptors 7 and 8 Selectivity and Enhanced Cytokine Induction." Journal of Medicinal Chemistry 57.2 (2014): 339-347.
Formula: C20H26N4O3
Interested in this reagent? E-mail us at info@reagency.co and let us know.
Systematic Name: methyl 4-amino-2-butyl-1-(2-hydroxy-2-methylpropyl)-1H-imidazo[4,5-c]quinoline-7-carboxylate
Molecular Weight: 370.45
PMID: 24383475
Reference: Schiaffo, Charles E., et al. "Structure–Activity Relationship Analysis of Imidazoquinolines with Toll-like Receptors 7 and 8 Selectivity and Enhanced Cytokine Induction." Journal of Medicinal Chemistry 57.2 (2014): 339-347.
Formula: C20H26N4O3
Interested in this reagent? E-mail us at info@reagency.co and let us know.
Tags: TLR7, TLR8, immunity, RGNCY-0003, vaccine